PXD041934

PXD041934 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Bile acids at host-Enterobacteriaceae interface
Description	The intestinal mucosa of inflammatory bowel disease (IBD) patients is enriched with Enterobacteriaceae members. Concurrently, there is elevated bile acid (BA) bioavailability in the colons of IBD patients. Whether enhanced BA levels contribute to the bloom of Enterobacteriaceae members in IBD patients remains unexplored.
HostingRepository	PRIDE
AnnounceDate	2025-10-08
AnnouncementXML	Submission_2025-10-08_06:31:00.524.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jenny Moon
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Bruker Daltonics timsTOF series

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-05-02 17:45:47	ID requested
⏵ 1	2025-10-08 06:31:01	announced

Publication List

Holani R, Bar-Yoseph H, Krekhno Z, Serapio-Palacios A, Moon KM, Stacey RG, Donald KA, Deng W, Bressler B, Maga, ñ, a AA, Foster LJ, Atser MG, Johnson JD, Finlay B, Bile acid-induced metabolic changes in the colon promote Enterobacteriaceae expansion and associate with dysbiosis in Crohn's disease. Sci Signal, 17(867):eadl1786(2024) [pubmed]
10.1126/scisignal.adl1786;

Holani R, Bar-Yoseph H, Krekhno Z, Serapio-Palacios A, Moon KM, Stacey RG, Donald KA, Deng W, Bressler B, Maga, ñ, a AA, Foster LJ, Atser MG, Johnson JD, Finlay B, Bile acid-induced metabolic changes in the colon promote Enterobacteriaceae expansion and associate with dysbiosis in Crohn's disease. Sci Signal, 17(867):eadl1786(2024) [pubmed]

10.1126/scisignal.adl1786;

Keyword List

submitter keyword: Enterobacteriaceae, Bile acids, Mitochondrial dysfunction,Crohn’s disease

submitter keyword: Enterobacteriaceae, Bile acids, Mitochondrial dysfunction,Crohn’s disease

Contact List

Leonard J. Foster
contact affiliation	Biochemistry and Molecular Biology, Michael Smith Laboratories, University of British Columbia, Canada
contact email	foster@msl.ubc.ca
lab head
Jenny Moon
contact affiliation	University of British Columbia
contact email	kyungmee@mail.ubc.ca
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD041934
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD041934

PRIDE project URI

Repository Record List

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