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PXD041908

PXD041908 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTargeting APEX2 to the mRNA encoding fatty acid synthase β in yeast identifies proteins that bind and control its translational efficiency in the cell cycle
DescriptionTo understand how the translation of FAS1, encoding fatty acid synthase, peaks late in the cell cycle, we identified proteins that bind the FAS1 transcript in a cell cycle-dependent manner. We used dCas13d-APEX2 fusions to target FAS1 and label nearby proteins, which were then identified by mass spectrometry.
HostingRepositoryPRIDE
AnnounceDate2024-05-24
AnnouncementXMLSubmission_2024-05-24_02:39:43.393.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMichael Polymenis
SpeciesList scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-05-01 09:52:08ID requested
12024-05-24 02:39:44announced
Publication List
10.1091/mbc.e23-05-0166;
Blank HM, Griffith WP, Polymenis M, in yeast identifies interacting proteins that control its abundance in the cell cycle. Mol Biol Cell, 34(13):br20(2023) [pubmed]
Keyword List
submitter keyword: yeast
LC-MS/MS
proximity labeling
Contact List
Michael Polymenis
contact affiliationDepartment of Biochemistry and Biophysics Texas A&M University
contact emailpolymenis@tamu.edu
lab head
Michael Polymenis
contact affiliationTexas A&M University
contact emailpolymenis@tamu.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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