PXD041864

PXD041864 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Ochrogaster lunifer setae proteome
Description	Ochrogaster lunifer (Lepidoptera: Notodontidae) is an Australian processionary caterpillar with detachable urticating setae that have a defensive function. These true setae induce inflammation when they contact human skin, and equine foetal loss syndrome if they are accidentally ingested by gravid horses. We used transcriptomics and proteomics to identify proteins and peptides present in and on urticating setae, which may include toxins that contribute to inflammation and/or foetal loss syndromes. This process identified 37 putative toxins, including multiple homologues of the honeybee venom peptide secapin, and proteins with similarity to odorant binding proteins, arylphorins, and the insect immune modulator Diedel. This work identifies candidate molecules that may contribute to the adverse effects of processionary caterpillar setae on human and animal health.
HostingRepository	PRIDE
AnnounceDate	2024-07-30
AnnouncementXML	Submission_2024-07-29_16:17:29.129.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Andrew Walker
SpeciesList	scientific name: Ochrogaster lunifer; NCBI TaxID: 319761;
ModificationList	amidated residue
Instrument	TripleTOF 5600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-04-27 20:35:37	ID requested
⏵ 1	2024-07-29 16:17:29	announced

Publication List

Walker AA, Perkins LE, Battisti A, Zalucki MP, King GF, Proteome of urticating setae of Ochrogaster lunifer, a processionary caterpillar of medical and veterinary importance, including primary structures of putative toxins. Proteomics, 23(20):e2300204(2023) [pubmed]
10.1002/pmic.202300204;

Walker AA, Perkins LE, Battisti A, Zalucki MP, King GF, Proteome of urticating setae of Ochrogaster lunifer, a processionary caterpillar of medical and veterinary importance, including primary structures of putative toxins. Proteomics, 23(20):e2300204(2023) [pubmed]

10.1002/pmic.202300204;

Keyword List

ProteomeXchange project tag: Toxicoproteomics (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: processionary caterpillar
equine amnionitis and foetal loss
Lepidoptera
toxin

ProteomeXchange project tag: Toxicoproteomics (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project

submitter keyword: processionary caterpillar

equine amnionitis and foetal loss

Lepidoptera

toxin

Contact List

Glenn King
contact affiliation	Institute for Molecular Biosciences, The University of Queensland
contact email	glenn.king@imb.uq.edu.au
lab head
Andrew Walker
contact affiliation	University of Queensland
contact email	a.walker@uq.edu.au
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD041864
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD041864

PRIDE project URI

Repository Record List

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