PXD041839

PXD041839 is an original dataset announced via ProteomeXchange.

Title	Proteomics of Staphylococcus aureus
Description	Tannic acid (TA) and punicalagin(P), which both are polyphenols, have attracted much attention in recent years due to its extensive physiological activities, which include antioxidant, antitumoral, antimicrobial and anti-inflammatory actions. Previous work revealed that TA has an inhibitory effect on a variety of bacteria, including S. aureus, Salmonella, and Lactobacillus. Previous researches suggested that TA inhibited bacterial growth by chelating ions from the culture medium, and by inhibiting fatty acid synthesis through suppression of the activity of β-ketoacyl-ACP reductase, or by interfering with cell wall integrity. However, the mechanisms underlying the inhibitory effect of TA and P on S.aureus have not been assessed comprehensively. Therefore, the present study combined transcriptome and proteome data to analyze the molecular mechanisms of TA and P in S. aureus.
HostingRepository	iProX
AnnounceDate	2023-04-26
AnnouncementXML	Submission_2023-09-06_23:56:56.106.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jing Wang
SpeciesList	scientific name: Staphylococcus aureus; NCBI TaxID: 1280;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2023-04-26 19:20:26	ID requested
1	2023-06-01 05:35:13	announced
⏵ 2	2023-09-06 23:56:57	announced	2023-09-07: Update publication information.

Wang J, Sheng Z, Liu Y, Chen X, Wang S, Yang H, . Front Pharmacol, 14():1178177(2023) [pubmed]

submitter keyword: Tannic acid, punicalagin, S. aureus, proteome

Jing Wang
contact affiliation	Jiangsu Agri-animal Husbandry Vocational College
contact email	kenhtsjj@163.com
lab head
Jing Wang
contact affiliation	Jiangsu Agri-animal Husbandry Vocational College
contact email	kenhtsjj@163.com
dataset submitter

iProX dataset URI