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PXD041732

PXD041732 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleBioID screen for Uhrf2 interactors in AML12 cells
DescriptionWe identified the ubiquitin ligase Uhrf2 as an important regulator of liver regeneration. To gain insight into the mechanisms of action of Uhrf2 in hepatocytes, we searched for Uhrf2 interactors in the AML12 hepatocyte cell line using BioID interaction screening. This resulted in the identification of major chromatin remodelling proteins as Uhrf2 interactors.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:48:24.268.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterCoenraad Frederik Slabber
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-04-22 07:45:10ID requested
12023-06-01 07:43:52announced
22023-11-14 08:48:26announced2023-11-14: Updated project metadata.
Publication List
Slabber CF, Bachofner M, Speicher T, Kuklin A, Fearon AE, Padrissa-Alt, é, s S, Bogorad R, Horv, á, th Rudigier C, W, ü, st D, Krautbauer S, H, ö, ring M, Liebisch G, Anderson DG, Wolfrum C, Auf dem Keller U, Werner S, The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration. Sci Signal, 16(787):eade8029(2023) [pubmed]
Keyword List
submitter keyword: Q-Exactive HF,Mouse, BioID, AML12 cells
Contact List
Prof. Dr. Sabine Werner
contact affiliationDepartment of Biology, ETH Zurich
contact emailsabine.werner@biol.ethz.ch
lab head
Coenraad Frederik Slabber
contact affiliationETH Zurich
contact emailerik.slabber@biol.ethz.ch
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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