PXD041732 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | BioID screen for Uhrf2 interactors in AML12 cells |
Description | We identified the ubiquitin ligase Uhrf2 as an important regulator of liver regeneration. To gain insight into the mechanisms of action of Uhrf2 in hepatocytes, we searched for Uhrf2 interactors in the AML12 hepatocyte cell line using BioID interaction screening. This resulted in the identification of major chromatin remodelling proteins as Uhrf2 interactors. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:48:24.268.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Coenraad Frederik Slabber |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | monohydroxylated residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-04-22 07:45:10 | ID requested | |
1 | 2023-06-01 07:43:52 | announced | |
⏵ 2 | 2023-11-14 08:48:26 | announced | 2023-11-14: Updated project metadata. |
Publication List
Slabber CF, Bachofner M, Speicher T, Kuklin A, Fearon AE, Padrissa-Alt, é, s S, Bogorad R, Horv, á, th Rudigier C, W, ü, st D, Krautbauer S, H, ö, ring M, Liebisch G, Anderson DG, Wolfrum C, Auf dem Keller U, Werner S, The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration. Sci Signal, 16(787):eade8029(2023) [pubmed] |
Keyword List
submitter keyword: Q-Exactive HF,Mouse, BioID, AML12 cells |
Contact List
Prof. Dr. Sabine Werner |
contact affiliation | Department of Biology, ETH Zurich |
contact email | sabine.werner@biol.ethz.ch |
lab head | |
Coenraad Frederik Slabber |
contact affiliation | ETH Zurich |
contact email | erik.slabber@biol.ethz.ch |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD041732 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD041732
- Label: PRIDE project
- Name: BioID screen for Uhrf2 interactors in AML12 cells