PXD041573

PXD041573 is an original dataset announced via ProteomeXchange.

Title	Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2
Description	Otu2-driven deubiquitylation of ribosomal protein eS7 impacts translational efficiency. Here, authors provide the molecular basis for recognition of monoubiquitinated eS7 on 40S and give mechanistic insights into Otu2’s role in translation reset. In this context quantitative mass spectrometry analyses of OTU2 and UBP3 pulldowns were performed.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:48:14.364.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Thomas Fröhlich
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-04-17 01:27:25	ID requested
1	2023-05-12 23:12:13	announced
⏵ 2	2023-11-14 08:48:22	announced	2023-11-14: Updated project metadata.

Ikeuchi K, Ivic N, Buschauer R, Cheng J, Fr, ö, hlich T, Matsuo Y, Berninghausen O, Inada T, Becker T, Beckmann R, Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14(1):2730(2023) [pubmed]

submitter keyword: pulldown,Translation, ubiquitination, OTU2, UBP3

Thomas Fröhlich
contact affiliation	Ludwig-Maximilians-Universität München Gene Center Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25
contact email	frohlich@genzentrum.lmu.de
lab head
Thomas Fröhlich
contact affiliation	Laboratory for Functional Genome Analysis Gene Center Munich Ludwig-Maximilians-Universität Munich (LMU) Feodor-Lynen-Str. 25 81377 Munich Germany
contact email	frohlich@genzentrum.lmu.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD041573

PRIDE project URI

• PRIDE
  1. PXD041573
     1. Label: PRIDE project
     2. Name: Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2