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PXD041543

PXD041543 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIdentifying convergent pathomechanisms in ALS using hiPSC-derived motor neurons
DescriptionAmyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease mainly affecting upper and lower motoneurons (MNs). In the last decades, several genes have been associated to the familial form of this disorder (fALS), thus depicting an extremely complex pathogenic landscape. The aim of this study was to identify convergent molecular underpinnings shared by ALS cases characterized by mutations in different genes using human induced pluripotent stem cells (hiPSCs).
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:58:48.461.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMirita Franz-Wachtel
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF; Orbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-04-14 07:02:23ID requested
12023-07-28 05:49:50announced
22024-10-22 05:58:48announced2024-10-22: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: synapse,ALS, hiPSC, motor neurons
Contact List
Alberto Catanese
contact affiliationCell biology of neurodegenerative diseases Institute of Anatomy and Cell Biology Ulm University Ulm Germany
contact emailalberto.catanese@uni-ulm.de
lab head
Mirita Franz-Wachtel
contact affiliationProteome Center Tuebingen
contact emailmirita.franz@uni-tuebingen.de
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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