PXD041543

PXD041543 is an original dataset announced via ProteomeXchange.

Title	Identifying convergent pathomechanisms in ALS using hiPSC-derived motor neurons
Description	Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease mainly affecting upper and lower motoneurons (MNs). In the last decades, several genes have been associated to the familial form of this disorder (fALS), thus depicting an extremely complex pathogenic landscape. The aim of this study was to identify convergent molecular underpinnings shared by ALS cases characterized by mutations in different genes using human induced pluripotent stem cells (hiPSCs).
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:58:48.461.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mirita Franz-Wachtel
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF; Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2023-04-14 07:02:23	ID requested
1	2023-07-28 05:49:50	announced
⏵ 2	2024-10-22 05:58:48	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: synapse,ALS, hiPSC, motor neurons

Alberto Catanese
contact affiliation	Cell biology of neurodegenerative diseases Institute of Anatomy and Cell Biology Ulm University Ulm Germany
contact email	alberto.catanese@uni-ulm.de
lab head
Mirita Franz-Wachtel
contact affiliation	Proteome Center Tuebingen
contact email	mirita.franz@uni-tuebingen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD041543

PRIDE project URI

• PRIDE
  1. PXD041543
     1. Label: PRIDE project
     2. Name: Identifying convergent pathomechanisms in ALS using hiPSC-derived motor neurons