PXD041543 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Identifying convergent pathomechanisms in ALS using hiPSC-derived motor neurons |
Description | Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease mainly affecting upper and lower motoneurons (MNs). In the last decades, several genes have been associated to the familial form of this disorder (fALS), thus depicting an extremely complex pathogenic landscape. The aim of this study was to identify convergent molecular underpinnings shared by ALS cases characterized by mutations in different genes using human induced pluripotent stem cells (hiPSCs). |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:58:48.461.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Mirita Franz-Wachtel |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF; Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-04-14 07:02:23 | ID requested | |
1 | 2023-07-28 05:49:50 | announced | |
⏵ 2 | 2024-10-22 05:58:48 | announced | 2024-10-22: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: synapse,ALS, hiPSC, motor neurons |
Contact List
Alberto Catanese |
contact affiliation | Cell biology of neurodegenerative diseases Institute of Anatomy and Cell Biology Ulm University Ulm Germany |
contact email | alberto.catanese@uni-ulm.de |
lab head | |
Mirita Franz-Wachtel |
contact affiliation | Proteome Center Tuebingen |
contact email | mirita.franz@uni-tuebingen.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD041543 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD041543
- Label: PRIDE project
- Name: Identifying convergent pathomechanisms in ALS using hiPSC-derived motor neurons