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PXD041416

PXD041416 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic profiling of eIF3a conditional knockout mice
DescriptionIn this study, a Cre-loxP system was used to generate eIF3a conditional knockout mice. Tandem mass tag (TMT) labeling with LC-MS/MS analysis was used to identify differentially expressed proteins (DEPs) in fat, lungs, skin, and spleen tissue of the eIF3a knockout mice and controls. Bioinformatics analysis was then used to explore the functions and molecular signaling pathways of these protein landscapes.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_09:03:35.421.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterWei Zhuo
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-04-09 05:55:48ID requested
12023-07-20 11:55:13announced
22023-11-14 09:03:36announced2023-11-14: Updated project metadata.
Publication List
Zhuo W, Chen J, Jiang S, Zheng J, Huang H, Xie P, Li W, Lei M, Yin J, Gao Y, Liu Z, Proteomic profiling of eIF3a conditional knockout mice. Front Mol Biosci, 10():1160063(2023) [pubmed]
Keyword List
ProteomeXchange project tag: Cancer (B/D-HPP)
submitter keyword: eIF3a, proteomics, knockout mice, protein landscape, oxidative stress
Contact List
Zhaoqian Liu
contact affiliationXiangya Hospital, Central South University
contact emailzqliu@csu.edu.cn
lab head
Wei Zhuo
contact affiliationcsu
contact emailmvp0811@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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