PXD041288

PXD041288 is an original dataset announced via ProteomeXchange.

Title	A high-quality resource of serum proteomic data from WMLs patients and model rats
Description	White matter lesions (WMLs) are common in older adults and can lead to cognitive decline and dementia. The neuroinflammation caused by chronic cerebral hypoperfusion (CCH) significantly contributes to WMLs. Peripherally derived mononuclear macrophages are implicated in the development of neuroinflammation. In order to further explore the blood molecules that promote the migration of peripheral monocytes to the site of white matter damage, we applied DIA quantitative proteomic approach to analyze differential serum proteins in WMLs patients and model rats.
HostingRepository	iProX
AnnounceDate	2023-04-01
AnnouncementXML	Submission_2023-11-15_19:37:15.340.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuhan Wang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606; scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2023-04-02 20:04:15	ID requested
⏵ 1	2023-11-15 19:37:15	announced

Dataset with its publication pending

submitter keyword: chronic cerebral hypoperfusion, white matter lesions, leukoaraiosis, vascular cognitive impairment, cerebral ischemia, vascular dementia, serum proteome, DIA

Wen Huang
contact affiliation	Xinqiao Hospital, the Army Medical University (Third Military Medical University)
contact email	huangmy0603@163.com
lab head
Yuhan Wang
contact affiliation	Xinqiao Hospital, the Army Medical University (Third Military Medical University)
contact email	1403488136@qq.com
dataset submitter

iProX dataset URI