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PXD041259

PXD041259 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAntler stem cell-conditioned medium data independent acquisition
DescriptionThe process of chondrogenesis in deer antlers is very similar to that of mammalian cartilage formation. Antlers can regenerate at an alarming rate (up to 2 cm per day). To meet the rapid growth of antlers, paracrine factors play an important role. These paracrine factors promote the proliferation and growth of chondrocytes, regulate cartilage development and modulate cartilage phenotype. The application of stem cell paracrine factors for the treatment of cartilage defects avoids the problems of immunocompatibility, tumorigenicity, embolization, and infection. This study demonstrates that ASC-CM can effectively repair cartilage defects using in vitro and in vivo methods, providing a suitable cell source and pathway for cartilage repair and providing ideas for mechanisms to promote cartilage regeneration.
HostingRepositoryPRIDE
AnnounceDate2024-02-12
AnnouncementXMLSubmission_2024-02-12_09:03:44.095.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterjue zhou
SpeciesList scientific name: Cervus elaphus hippelaphus; NCBI TaxID: 46360;
ModificationListNo PTMs are included in the dataset
InstrumentThermo Fisher Scientific instrument model
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-03-31 11:12:50ID requested
12024-02-12 09:03:44announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Data independent acquisition,Deer,Antler stem cell-conditioned medium, Antler stem cell
Contact List
Hongmei Sun
contact affiliationChinese Academy of Agricultural Sciences
contact emailsunhongmei@caas.cn
lab head
jue zhou
contact affiliationChinese Academy of Agricultural Sciences
contact emailzhoujue819@outlook.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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