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PXD041235

PXD041235 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDeorphanization of neuropeptide GPCRs in Nematostella vectensis
DescriptionThe aim of this part of the wider project is to identify neuropeptide precursors, investigate cleavage sites on neuropeptide precursors and predict mature peptides in the sea anemone Nematostella vectensis. This was done to create a synthetic library of N. vectensis neuropeptides which were then used to test neuropeptide receptor candidates for activation by the different peptides.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:35:19.720.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD041235
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterAmanda Kieswetter
SpeciesList scientific name: Nematostella vectensis; NCBI TaxID: 45351;
ModificationListamidated residue; 2-pyrrolidone-5-carboxylic acid (Glu); half cystine; 2-pyrrolidone-5-carboxylic acid (Gln); monohydroxylated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-03-31 00:47:00ID requested
12024-04-08 01:10:37announced
22024-10-22 06:35:20announced2024-10-22: Updated project metadata.
Publication List
10.7554/ELIFE.90674.1;
10.6019/PXD041235;
Keyword List
submitter keyword: deorphanization, GPCRs, cleavage sites, cnidaria,neuropeptides, Nematostella, precursors
Contact List
Gáspár Jékely
contact affiliationLiving Systems Institute, University of Exeter, Exeter, England, United Kingdom
contact emailG.Jekely@exeter.ac.uk
lab head
Amanda Kieswetter
contact affiliationKU Leuven
contact emailamanda.kieswetter@kuleuven.be
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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