PXD041235

PXD041235 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Deorphanization of neuropeptide GPCRs in Nematostella vectensis
Description	The aim of this part of the wider project is to identify neuropeptide precursors, investigate cleavage sites on neuropeptide precursors and predict mature peptides in the sea anemone Nematostella vectensis. This was done to create a synthetic library of N. vectensis neuropeptides which were then used to test neuropeptide receptor candidates for activation by the different peptides.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:35:19.720.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD041235
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Amanda Kieswetter
SpeciesList	scientific name: Nematostella vectensis; NCBI TaxID: 45351;
ModificationList	amidated residue; 2-pyrrolidone-5-carboxylic acid (Glu); half cystine; 2-pyrrolidone-5-carboxylic acid (Gln); monohydroxylated residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-03-31 00:47:00	ID requested
1	2024-04-08 01:10:37	announced
⏵ 2	2024-10-22 06:35:20	announced	2024-10-22: Updated project metadata.

Publication List

10.7554/ELIFE.90674.1;
10.6019/PXD041235;

10.7554/ELIFE.90674.1;

10.6019/PXD041235;

Keyword List

submitter keyword: deorphanization, GPCRs, cleavage sites, cnidaria,neuropeptides, Nematostella, precursors

submitter keyword: deorphanization, GPCRs, cleavage sites, cnidaria,neuropeptides, Nematostella, precursors

Contact List

Gáspár Jékely
contact affiliation	Living Systems Institute, University of Exeter, Exeter, England, United Kingdom
contact email	G.Jekely@exeter.ac.uk
lab head
Amanda Kieswetter
contact affiliation	KU Leuven
contact email	amanda.kieswetter@kuleuven.be
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/04/PXD041235
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/04/PXD041235

PRIDE project URI

Repository Record List

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