PXD041156

PXD041156 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Clients of membrane-bound PDI family members
Description	The client-specificity of TMX3, TMX4 and TMX5 in cellula, was assessed by expressing mutant forms of the enzymes, where the last cysteine residue of the TMX’s CXXC catalytic sites has been mutated to alanine, which stabilizes the mixed disulfide that oxidoreductases establish with clients. Clients remain disulfide-bonded to the oxidoreductase and are identified upon co-immunoprecipitation and mass spectrometry analyses.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_09:01:04.689.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD041156
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Manfredo Quadroni
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive Plus

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-03-28 00:21:17	ID requested
1	2023-06-12 07:27:58	announced
⏵ 2	2023-11-14 09:01:05	announced	2023-11-14: Updated project metadata.

Publication List

10.6019/PXD041156;

10.6019/PXD041156;

Keyword List

submitter keyword: trapping mutants, Endoplasmic reticulum,Oxidoreductases, mixed disulfides

submitter keyword: trapping mutants, Endoplasmic reticulum,Oxidoreductases, mixed disulfides

Contact List

Maurizio Molinari
contact affiliation	Institute for Research in Biomedicine, Via Chiesa 5, 6500 Bellinzona, Switzerland
contact email	Maurizio.molinari@irb.usi.ch
lab head
Manfredo Quadroni
contact affiliation	University of Lausanne
contact email	manfredo.quadroni@unil.ch
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD041156
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD041156

PRIDE project URI

Repository Record List

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