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PXD041108

PXD041108 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleGlobal discovery of synapse proteins using multi-omic synaptic signatures
DescriptionBottom-up proteomics analysis of whole cell lysate and synaptosomes extracted from wild type and Cul3-haploinsufficient mouse cortex
HostingRepositoryPRIDE
AnnounceDate2026-03-09
AnnouncementXMLSubmission_2026-03-08_19:25:23.474.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJustin McKetney
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-03-25 22:15:39ID requested
12026-03-08 19:25:24announced
Publication List
10.1016/j.cels.2025.101204;
Mei Y, Gosztyla ML, Tan X, Dozier LE, Wilkinson B, McKetney J, Lee J, Chen M, Tsai D, Kopalle H, Gritsenko MA, Hartel N, Graham NA, Flores I, Gilmore-Hall SK, Xu S, Marquez CA, Liu SN, Fong D, Chen J, Licon K, Hong D, Wright SN, Kreisberg JF, Nott A, Smith RD, Qian WJ, Swaney DL, Iakoucheva LM, Krogan NJ, Patrick GN, Zhou Y, Feng G, Coba MP, Yeo GW, Ideker T, Integrated multi-omic characterizations of the synapse reveal RNA processing factors and ubiquitin ligases associated with neurodevelopmental disorders. Cell Syst, 16(4):101204(2025) [pubmed]
Keyword List
submitter keyword: synaptosome,LC-MSMS
Contact List
Nevan J Krogan
contact affiliationQBI Director and Professor in Cellular and Molecular Pharmacology, UCSF
contact emailnevan.krogan@ucsf.edu
lab head
Justin McKetney
contact affiliationUniversity of California, San Francisco
contact emailjustinmcketney@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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