PXD041023

PXD041023 is an original dataset announced via ProteomeXchange.

Title	A low-input proteomic analysis of mouse maternal-to-zygotic transition
Description	Maternal-to-zygotic transition (MZT) is a conserved and fundamental process during which the maternal environment of oocyte transits to the zygotic genome driven expression program, and terminally differentiated oocyte and sperm are reprogrammed to totipotency. It is initiated by maternal mRNAs and proteins during the period of zygotic genome quiescence after fertilization, followed by a gradual switch to zygotic genome activation and accompanied by clearance of maternal RNAs and proteins. A key question for embryonic development is how MZT process is regulated. Here we used a low-input proteomic analysis to measure the proteomic dynamics during early development of mouse maternal-to-zygotic transition.
HostingRepository	PRIDE
AnnounceDate	2023-03-27
AnnouncementXML	Submission_2023-03-27_08:59:29.350.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	LeiGu
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2023-03-22 02:34:22	ID requested
⏵ 1	2023-03-27 08:59:29	announced

Dataset with its publication pending

submitter keyword: zygotic genome activation, maternal-to-zygotic transition,low-input proteomic technology, mouse embryo, mouse oocyte

ChenLi
contact affiliation	Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China
contact email	cli@shsmu.edu.cn
lab head
LeiGu
contact affiliation	Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine
contact email	summerrushing@163.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD041023
     1. Label: PRIDE project
     2. Name: A low-input proteomic analysis of mouse maternal-to-zygotic transition