PXD041001

PXD041001 is an original dataset announced via ProteomeXchange.

Title	Arabidopsis thaliana polyQ - interactors
Description	We've demonstrated that plants are resistant to the overexpression of polyglutamine (polyQ) extended proteins that cause protein aggregation and Huntington's disease in human cells. To investigate which proteins, maintain polyQ proteins correctly folded and avoid polyQ aggregates in plant cells. Our goal is to identify therapeutic candidate proteins that can potentially be used to treat Huntington's disease in human cell models.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:54:05.817.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Prerana Wagle
SpeciesList	scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702;
ModificationList	monohydroxylated residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2023-03-21 03:21:10	ID requested
1	2023-07-17 04:32:14	announced
⏵ 2	2024-10-22 05:54:06	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: Arabidopsis thaliana, polyQ-extended proteins,Huntington's disease

David Vilchez
contact affiliation	CECAD Forschungszentrum, Joseph-Stelzmann-Str. 26, 50931 Köln
contact email	dvilchez@uni-koeln.de
lab head
Prerana Wagle
contact affiliation	CECAD Research Center
contact email	proteomics-facility@uni-koeln.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD041001

PRIDE project URI

• PRIDE
  1. PXD041001
     1. Label: PRIDE project
     2. Name: Arabidopsis thaliana polyQ - interactors