PXD040989
PXD040989 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Apoptotic vesicles resist oxidative damage in noise-induced hearing loss through activation of FOXO3a-SOD2 pathway |
Description | The purpose of this study is to investigate the therapeutic effect of MSC-derived apoVs treatment on NIHL and the potential mechanism of resisting oxidative stress damage in hair cells, as well as the distribution of apoptotic vesicles in the inner ear. The study provided a new direction for the treatment of noise-induced hearing loss and inner ear delivery. |
HostingRepository | iProX |
AnnounceDate | 2023-03-20 |
AnnouncementXML | Submission_2023-04-24_19:43:51.391.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Xiaotong Huang |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | acetylated residue; S-carboxamidomethyl-L-cysteine; oxidation |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-03-20 19:25:50 | ID requested | |
1 | 2023-03-20 19:26:18 | announced | |
⏵ 2 | 2023-04-24 19:43:52 | announced | 2023-04-25: Update publication information. |
Publication List
Huang X, Kou X, Zhan T, Wei G, He F, Mao X, Yang H, Apoptotic vesicles resist oxidative damage in noise-induced hearing loss through activation of FOXO3a-SOD2 pathway. Stem Cell Res Ther, 14(1):88(2023) [pubmed] |
Keyword List
submitter keyword: mesenchymal stem cell, apoptotic vesicles, oxidative stress, noise-induced hearing loss, mitochondrial superoxide dismutase 2 (SOD2) |
Contact List
Haidi Yang | |
---|---|
contact affiliation | Department of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University |
contact email | yanghd@mail.sysu.edu.cn |
lab head | |
Xiaotong Huang | |
contact affiliation | Sun Yat-sen Memorial Hospital, Sun Yat-sen University |
contact email | huangxt26@mail2.sysu.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |