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PXD040989

PXD040989 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleApoptotic vesicles resist oxidative damage in noise-induced hearing loss through activation of FOXO3a-SOD2 pathway
DescriptionThe purpose of this study is to investigate the therapeutic effect of MSC-derived apoVs treatment on NIHL and the potential mechanism of resisting oxidative stress damage in hair cells, as well as the distribution of apoptotic vesicles in the inner ear. The study provided a new direction for the treatment of noise-induced hearing loss and inner ear delivery.
HostingRepositoryiProX
AnnounceDate2023-03-20
AnnouncementXMLSubmission_2023-04-24_19:43:51.391.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXiaotong Huang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListacetylated residue; S-carboxamidomethyl-L-cysteine; oxidation
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-03-20 19:25:50ID requested
12023-03-20 19:26:18announced
22023-04-24 19:43:52announced2023-04-25: Update publication information.
Publication List
Huang X, Kou X, Zhan T, Wei G, He F, Mao X, Yang H, Apoptotic vesicles resist oxidative damage in noise-induced hearing loss through activation of FOXO3a-SOD2 pathway. Stem Cell Res Ther, 14(1):88(2023) [pubmed]
Keyword List
submitter keyword: mesenchymal stem cell, apoptotic vesicles, oxidative stress, noise-induced hearing loss, mitochondrial superoxide dismutase 2 (SOD2)
Contact List
Haidi Yang
contact affiliationDepartment of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
contact emailyanghd@mail.sysu.edu.cn
lab head
Xiaotong Huang
contact affiliationSun Yat-sen Memorial Hospital, Sun Yat-sen University
contact emailhuangxt26@mail2.sysu.edu.cn
dataset submitter
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