PXD040965
PXD040965 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | A Proteomic Approach to Distinguish Leptomeningeal Metastasis in Lung Adenocarcinoma Patients |
Description | Based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) investigation of cere-brospinal fluid (CSF), we prospectively characterized proteins in CSF samples of 36 lung adeno-carcinoma patients, including 19 LM patients and 17 non-LM patients. We identified 290 signifi-cantly differentially expressed proteins (DEPs). In this study, we applied proteomic methods to develop a model to assist diagnosis of LM in lung adenocarcinoma cancer and identified an important biomarker, TSP-2. |
HostingRepository | iProX |
AnnounceDate | 2023-03-20 |
AnnouncementXML | Submission_2023-08-31_19:19:04.637.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Chuan Jin |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-03-19 20:09:33 | ID requested | |
⏵ 1 | 2023-08-31 19:19:04 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Lung adenocarcinoma, Leptomeningeal metastasis, Biomarkers, Cerebrospinal fluid, LC-MS/MS |
Contact List
Xiaolei Wu | |
---|---|
contact affiliation | Tianjin Key Laboratory of Clinical Multiomics |
contact email | xiaolei.wu@proteint.com |
lab head | |
Chuan Jin | |
contact affiliation | Tianjin Key Laboratory of Clinical Multiomics |
contact email | seq@proteint.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |