PXD040829

PXD040829 is an original dataset announced via ProteomeXchange.

Title	Proteomic profile of P. brasiliensis yeasts recovered from granulomatous lesions of C57BL/6 WT mice
Description	C57BL/6 WT mice were infected with 1x10^6 P. brasiliensis yeasts. After 8 weeks and 12 weeks of infection the animals were euthanized and the granulomatous lesions were recovered. Then, the yeasts were recovered and cultivated in a rich medium. After cultivation the yeasts proteins were extracted, digested with trypsin and analyzed by LC-MS/MS. The data show an induced metabolism by the recovered yeasts, with a higher abundance of proteins related to energy metabolism, lipid metabolism, nucleotide metabolism, amino acid metabolism. Additionally there is a higher abundance of some virulence factor
HostingRepository	PRIDE
AnnounceDate	2023-10-23
AnnouncementXML	Submission_2023-10-23_06:23:02.669.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	BrunoBorges
SpeciesList	scientific name: Paracoccidioides brasiliensis (strain Pb18); NCBI TaxID: 502780;
ModificationList	acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2023-03-13 14:03:27	ID requested
⏵ 1	2023-10-23 06:23:03	announced

Dataset with its publication pending

submitter keyword: Paracoccidioidomycosis

granuloma

proteomic

Paracoccidioides brasiliensis

Flávio VieiraLoures
contact affiliation	Federal University of São Paulo - Institute of Science and Technology - Applied Immunology Lab
contact email	loures@unifesp.br
lab head
BrunoBorges
contact affiliation	UNIFESP
contact email	brumonborges@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD040829

PRIDE project URI

• PRIDE
  1. PXD040829
     1. Label: PRIDE project
     2. Name: Proteomic profile of P. brasiliensis yeasts recovered from granulomatous lesions of C57BL/6 WT mice