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PXD040745

PXD040745 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleChanges in cellular protein levels of the sgs1Δ mutant vs wildtype
DescriptionUsing quantitative proteomics in chromatin-enriched fractions, we have identified changes in the cellular response of cells lacking Sgs1, the yeast RecQ-like DNA helicase involved in homologous recombination. Primarily, we have identified upregulation of antioxidant enzymes such as Sod2 and Tsa1, compared to the wildtype cells. This analysis identifies an oxidative stress phenotype in cells lacking Sgs1.
HostingRepositoryPRIDE
AnnounceDate2023-08-07
AnnouncementXMLSubmission_2023-08-07_07:07:21.685.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDaleChaput
SpeciesList scientific name: Saccharomyces cerevisiae S228; NCBI TaxID: 1196866;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-03-09 18:10:55ID requested
12023-08-07 07:07:22announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: SILAC-MS,Yeast, Sgs1, chromatin
Contact List
KristinaSchmidt
contact affiliationProfessor, Department of Molecular Biosciences, University of South Florida
contact emailkschmidt@usf.edu
lab head
DaleChaput
contact affiliationUniversity of South Florida
contact emailchaput@usf.edu
dataset submitter
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Dataset FTP location
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