PXD040745 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Changes in cellular protein levels of the sgs1Δ mutant vs wildtype |
Description | Using quantitative proteomics in chromatin-enriched fractions, we have identified changes in the cellular response of cells lacking Sgs1, the yeast RecQ-like DNA helicase involved in homologous recombination. Primarily, we have identified upregulation of antioxidant enzymes such as Sod2 and Tsa1, compared to the wildtype cells. This analysis identifies an oxidative stress phenotype in cells lacking Sgs1. |
HostingRepository | PRIDE |
AnnounceDate | 2023-08-07 |
AnnouncementXML | Submission_2023-08-07_07:07:21.685.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | DaleChaput |
SpeciesList | scientific name: Saccharomyces cerevisiae S228; NCBI TaxID: 1196866; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-03-09 18:10:55 | ID requested | |
⏵ 1 | 2023-08-07 07:07:22 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: SILAC-MS,Yeast, Sgs1, chromatin |
Contact List
KristinaSchmidt |
contact affiliation | Professor, Department of Molecular Biosciences, University of South Florida |
contact email | kschmidt@usf.edu |
lab head | |
DaleChaput |
contact affiliation | University of South Florida |
contact email | chaput@usf.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD040745
- Label: PRIDE project
- Name: Changes in cellular protein levels of the sgs1Δ mutant vs wildtype