PXD040713
PXD040713 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | A pilot proteomic study on the mechanism of nutmeg-induced liver damage |
Description | Based on the proteomics and other biological analysis, we suggest that high-dose exposure to nutmeg may cause cholestasis and lipid metabolism disorders, thus leading to oxidative stress, glutathione depletion, lipid peroxidation, and hepatocyte damage associated apoptosis, which is mainly induced by cytochrome P450. |
HostingRepository | iProX |
AnnounceDate | 2020-12-10 |
AnnouncementXML | Submission_2023-03-08_23:45:19.169.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Lina Gao |
SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-03-08 23:45:11 | ID requested | |
⏵ 1 | 2023-03-08 23:45:19 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: nutmeg,liver,toxicity, proteomics |
Contact List
Lina Gao | |
---|---|
contact affiliation | China Medical University |
contact email | gaolina0114@sina.com |
lab head | |
Lina Gao | |
contact affiliation | China Medical University |
contact email | gaolina0114@sina.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |