PXD040680

PXD040680 is an original dataset announced via ProteomeXchange.

Title	Targeted Proteomics of Lung Squamous Cell Carcinomas
Description	To address the complexity of cancer, liquid chromatography-multiple reaction monitoring mass spectrometry (LC-MRM) panels provide the capability to quantify clinical biomarkers and emerging protein markers to establish the context of tumor phenotypes that provide highly relevant supporting information. The resulting targeted proteomics data will empower translational researchers to move protein biomarker panels through the process from discovery to clinical use. Here, targeted proteomics panel measurements provide pathway-level evaluations of key biological drivers (e.g., EGFR signaling), phenotypes (e.g., EMT) and the ability to quantify specific drug targets within the context of a sample cohort of lung squamous cell carcinomas.
HostingRepository	PanoramaPublic
AnnounceDate	2023-07-09
AnnouncementXML	Submission_2023-07-09_23:04:55.772.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	John Koomen
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	Carbamidomethyl; Oxidation; Label:13C(6)15N(2); Label:13C(6)15N(4)
Instrument	TSQ Altis

Revision	Datetime	Status	ChangeLog Entry
0	2023-03-07 23:04:58	ID requested
1	2023-04-04 08:32:40	announced
⏵ 2	2023-07-09 23:04:56	announced	: Added PubMed Id

Putty Reddy S, Alontaga AY, Welsh EA, Haura EB, Boyle TA, Eschrich SA, Koomen JM, Deciphering Phenotypes from Protein Biomarkers for Translational Research with PIPER. J Proteome Res, 22(6):2055-2066(2023) [pubmed]

submitter keyword: Lung Squamous Cell Carcinoma, multiple reaction monitoring

John Koomen
contact affiliation	Moffitt Cancer Center
contact email	john.koomen@moffitt.org
lab head
John Koomen
contact affiliation	Moffitt Cancer Center
contact email	john.koomen@moffitt.org
dataset submitter

Panorama Public dataset URI