PXD040620

PXD040620 is an original dataset announced via ProteomeXchange.

Title	DIA proteomics on mouse tissue to investigate the GAPDH redox switch
Description	The glycolytic enzyme GAPDH is equipped with a redox switch that rapidly and reversibly inactivates the enzyme in the presence of hydrogen peroxide. The physiological implications of the redox switch were investigated in C57BL/6NTac wildtype and GAPDH(T175A) knock-in mice generated by CRISPR/Cas9 genome editing.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:59:31.144.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Justus L. Großmann
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	timsTOF Pro 2

Revision	Datetime	Status	ChangeLog Entry
0	2023-03-06 06:01:05	ID requested
1	2023-04-10 09:03:26	announced
⏵ 2	2023-11-14 08:59:31	announced	2023-11-14: Updated project metadata.

Dataset with its publication pending

submitter keyword: heart, tissue, mus musculus, kidney, GAPDH,DIA-PASEF, mouse

Markus Ralser
contact affiliation	Department of Biochemistry, Charite Universitaetsmedizin Berlin, Germany
contact email	markus.ralser@charite.de
lab head
Justus L. Großmann
contact affiliation	Charité Universitätsmedizin Berlin
contact email	justus.grossmann@charite.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/04/PXD040620

PRIDE project URI

• PRIDE
  1. PXD040620
     1. Label: PRIDE project
     2. Name: DIA proteomics on mouse tissue to investigate the GAPDH redox switch