PXD040611

PXD040611 is an original dataset announced via ProteomeXchange.

Title	Diversity of cationic antimicrobial peptides in black cumin (Nigella sativa L.) seeds
Description	Black cumin (Nigella sativa L.) is known to possess a wide variety of antimicrobial peptides belonging to different structural families. Three novel antimicrobial peptides have been isolated from black cumin seeds. Two of them were attributed as members of the non-specific lipid transfer proteins family and one - as a defensin. We have made an attempt of using proteomic approach for novel antimicrobial peptides search in N. sativa seeds as well. The use of well established approach that includes extraction and fractionation stages remains relevant even in case of novel peptides search because the lacking of N. sativa genome data. Novel peptides demonstrate a spectrum of antimicrobial activity against plant pathogenic organisms that may cause economically important crop diseases. These results obtained allow considering these molecules as candidates to be applied in "next-generation" biopesticides development for agriculture use.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:56:29.086.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Elena Petrenko
SpeciesList	scientific name: Nigella sativa; NCBI TaxID: 555479;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-03-06 03:50:17	ID requested
1	2023-07-20 11:37:05	announced
2	2023-11-14 09:03:27	announced	2023-11-14: Updated project metadata.
⏵ 3	2024-10-22 05:56:29	announced	2024-10-22: Updated project metadata.

Barashkova AS, Smirnov AN, Zorina ES, Rogozhin EA, L.) Seeds. Int J Mol Sci, 24(9):(2023) [pubmed]

10.3390/ijms24098066;

submitter keyword: defensin, lipid transfer protein (LTP), Antimicrobial peptide (AMPs),Proteomic analysis, antimicrobial activity

Eugene Rogozhin
contact affiliation	Laboratory of neuroreceptors and neuroregulators, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, RAS, Moscow, Russia
contact email	rea21@list.ru
lab head
Elena Petrenko
contact affiliation	IBMC
contact email	el.petrenko@bk.ru
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD040611

PRIDE project URI

• PRIDE
  1. PXD040611
     1. Label: PRIDE project
     2. Name: Diversity of cationic antimicrobial peptides in black cumin (Nigella sativa L.) seeds