PXD040580

PXD040580 is an original dataset announced via ProteomeXchange.

Title	Intracellular peptides identified in plasma from SARS-CoV-2 infected patients
Description	Intracellular peptides (InPeps), generated by the orchestrated action of the proteasome and intracellular peptidases, were suggested to have both biological and pharmacological significance as G-protein coupled receptors (GPCR) agonists or inverse agonists. InPeps profile alters whenever there is a challenge or associated disease. In the present study, the relative concentration of InPeps was investigated in patients infected or not with SARS-CoV-2 virus. Altogether, the present results suggest variation of plasma relative concentration of specific InPeps, in a group of patients infected with SARS-CoV-2 virus compared to SARS-CoV-2 non-infected patients. Therefore, it is exciting to suggest that human plasma have InPeps that may be playing a yet unknown function in SARS-CoV-2 virus infection.
HostingRepository	PRIDE
AnnounceDate	2023-04-20
AnnouncementXML	Submission_2023-04-20_04:04:43.677.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD040580
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Luiz FelipeMartucci
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-03-03 08:10:29	ID requested
⏵ 1	2023-04-20 04:04:44	announced

10.6019/PXD040580;

submitter keyword: SARS-CoV-2, human, plasma, peptidome

Emer SuavinhoFerro
contact affiliation	Pharmacology Department, Biomedical Science Institute, University of Sao Paulo, Sao Paulo, Brazil
contact email	eferro@usp.br
lab head
Luiz FelipeMartucci
contact affiliation	University of São Paulo
contact email	felipemartucci@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/04/PXD040580

PRIDE project URI

• PRIDE
  1. PXD040580
     1. Label: PRIDE project
     2. Name: Intracellular peptides identified in plasma from SARS-CoV-2 infected patients