PXD040439 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | PQBP1-associated proteins spectrums in HEK-293 cells |
Description | Our study shows that deletion of the alternative splicing regulator PQBP1 in striatal progenitors resulted in defective striatal development due to impaired neurogenesis of spiny projection neurons (SPNs). Therefore, we further reveal that PQBP1 associated with components in splicing machinery by LC-MS/MS. These findings identify PQBP1 as a novel regulator in balancing striatal progenitor proliferation and differentiation. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:59:34.645.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Hao Xie |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-02-27 06:02:04 | ID requested | |
1 | 2023-03-16 01:57:10 | announced | |
⏵ 2 | 2023-11-14 08:59:35 | announced | 2023-11-14: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: PQBP1 |
HEK-293 cells |
LC-MSMS |
Contact List
Junhai Han |
contact affiliation | School of Life Science and Technology, Southeast University, Nanjing, Jiangsu Province, China |
contact email | junhaihan@seu.edu.cn |
lab head | |
Hao Xie |
contact affiliation | Southeast University |
contact email | hxie@seu.edu.cn |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD040439 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD040439
- Label: PRIDE project
- Name: PQBP1-associated proteins spectrums in HEK-293 cells