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PXD040439

PXD040439 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePQBP1-associated proteins spectrums in HEK-293 cells
DescriptionOur study shows that deletion of the alternative splicing regulator PQBP1 in striatal progenitors resulted in defective striatal development due to impaired neurogenesis of spiny projection neurons (SPNs). Therefore, we further reveal that PQBP1 associated with components in splicing machinery by LC-MS/MS. These findings identify PQBP1 as a novel regulator in balancing striatal progenitor proliferation and differentiation.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:59:34.645.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHao Xie
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-02-27 06:02:04ID requested
12023-03-16 01:57:10announced
22023-11-14 08:59:35announced2023-11-14: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: PQBP1
HEK-293 cells
LC-MSMS
Contact List
Junhai Han
contact affiliationSchool of Life Science and Technology, Southeast University, Nanjing, Jiangsu Province, China
contact emailjunhaihan@seu.edu.cn
lab head
Hao Xie
contact affiliationSoutheast University
contact emailhxie@seu.edu.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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