PXD040438

PXD040438 is an original dataset announced via ProteomeXchange.

Title	Covid Human plasma LC-MS Multiplatform Analyses Reveal Distinct Drivers of Systemic Pathogenesis in Adult Versus Pediatric Severe Acute COVID-19
Description	The adult data set. The pathogenesis of multi-organ dysfunction associated with severe acute SARS-CoV-2 infection remains poorly understood. Endothelial damage and microvascular thrombosis have been identified as drivers of COVID-19 severity, yet the mechanisms underlying these processes remain elusive. A multiomics approach identified alterations in analytes associated with fluid shear stress-responsive pathways in critically ill COVID-19 adults as compared to non-COVID critically ill adults.
HostingRepository	PRIDE
AnnounceDate	2023-03-06
AnnouncementXML	Submission_2023-03-06_09:50:10.036.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD040438
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	BlaineRoberts
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-27 06:01:45	ID requested
⏵ 1	2023-03-06 09:50:10	announced

10.6019/PXD040438;

submitter keyword: Human, LC-MS, COVID, plasma

Blanie R.Roberts
contact affiliation	Department of Biochemistry, Emory School of Medicine
contact email	blaine.roberts@emory.edu
lab head
BlaineRoberts
contact affiliation	Emory School of Medicine
contact email	blaine.roberts@emory.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD040438

PRIDE project URI

• PRIDE
  1. PXD040438
     1. Label: PRIDE project
     2. Name: Covid Human plasma LC-MS Multiplatform Analyses Reveal Distinct Drivers of Systemic Pathogenesis in Adult Versus Pediatric Severe Acute COVID-19