PXD040392

PXD040392 is an original dataset announced via ProteomeXchange.

Title	Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis.
Description	Project aim was to identify protein-protein interactions of the post-translationally modified form of alpha-synuclein. In situ proximity labeling (BAR) was used to enrich for protein-protein interactions. We performed BAR on wild-type and alpha-synuclein knockout olfactory bulb tissues. We include negative capture conditions, where the primary antibody was omitted.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:44:27.125.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Bryan Killinger
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-24 06:19:38	ID requested
1	2023-03-27 09:18:18	announced
⏵ 2	2023-11-14 08:44:29	announced	2023-11-14: Updated project metadata.

Killinger BA, Mercado G, Choi S, Tittle T, Chu Y, Brundin P, Kordower JH, Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis. NPJ Parkinsons Dis, 9(1):43(2023) [pubmed]

submitter keyword: Proteomics

neurodegeneration

vesicles

protein aggregation.

Bryan Andrew Killinger
contact affiliation	Assisstant professor. Graduate College. Rush University Medical Center.
contact email	bryan_killinger@rush.edu
lab head
Bryan Killinger
contact affiliation	Rush University Medical Center
contact email	bryan_killinger@rush.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD040392

PRIDE project URI

• PRIDE
  1. PXD040392
     1. Label: PRIDE project
     2. Name: Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis.