PXD040313

PXD040313 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Total and phosphoproteome analysis of effects of topoisomerase 1 and ATR inhibitors in small cell lung cancer nuclei
Description	Total and phosphoproteome analysis of effects of topoisomerase 1 (SN-38) and ATR (M1774) inhibitors in small cell lung cancer. Experiments performed in nuclear extract. See MetaData for more information.
HostingRepository	MassIVE
AnnounceDate	2024-06-14
AnnouncementXML	Submission_2024-06-14_09:23:28.402.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Lisa Jenkins
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Phospho; TMTpro
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-21 13:44:32	ID requested
⏵ 1	2024-06-14 09:23:29	announced

Publication List

Jo U, Arakawa Y, Zimmermann A, Taniyama D, Mizunuma M, Jenkins LM, Maity T, Kumar S, Zenke FT, Takebe N, Pommier Y, The Novel ATR Inhibitor M1774 Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs. Mol Cancer Ther, 23(7):911-923(2024) [pubmed]

Jo U, Arakawa Y, Zimmermann A, Taniyama D, Mizunuma M, Jenkins LM, Maity T, Kumar S, Zenke FT, Takebe N, Pommier Y, The Novel ATR Inhibitor M1774 Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs. Mol Cancer Ther, 23(7):911-923(2024) [pubmed]

Keyword List

submitter keyword: topoisomerase 1 inhibitor, ATR inhibitor, small cell lunch cancer, SN-38, M1774

submitter keyword: topoisomerase 1 inhibitor, ATR inhibitor, small cell lunch cancer, SN-38, M1774

Contact List

Lisa Jenkins
contact affiliation	NCI, NIH
contact email	jenkinsl@mail.nih.gov
lab head
Lisa Jenkins
contact affiliation	NCI
contact email	jenkinsl@mail.nih.gov
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v05/MSV000091336/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v05/MSV000091336/