PXD040311

PXD040311 is an original dataset announced via ProteomeXchange.

Title	SECRETORY PROTEOMIC RESPONSES OF ENDOMETRIAL EPITHELIAL CELLS TO TROPHOBLAST DERIVED EXTRACELLULAR VESICLES
Description	Synchronized cross talk between embryo and endometrium during pre-implantation period is critical for establishment of pregnancy. Extracellular vesicels(EVs) of both embryo and endometrial origin are known to be integral in regulating embryo maternal communication during this time. However, exact molecular signalling pathways or factors that regulate the embryo endometrial communication during pre-conception period remains elusive. Here in this study extracellular vesicles from trophoblast cells were shown to modulate endometrial epithelial cell secretome in favour of embryo implantation and embryo development.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_09:08:32.548.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	SUBHASHINI MUHANDIRAM MUHANDIRAM RALALAGE
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-21 02:46:10	ID requested
1	2023-10-24 12:04:18	announced
⏵ 2	2023-11-14 09:08:35	announced	2023-11-14: Updated project metadata.

Muhandiram S, Dissanayake K, Orro T, Godakumara K, Kodithuwakku S, Fazeli A, Secretory Proteomic Responses of Endometrial Epithelial Cells to Trophoblast-Derived Extracellular Vesicles. Int J Mol Sci, 24(15):(2023) [pubmed]

submitter keyword: Embryo, Extracellular Vesicles, LC-MS, Endometrium, Epithelial cells, Trophoblast cells, Secretome, Proteomics

Alireza Fazeli
contact affiliation	Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Kreutzwaldi 62, 51006, Tartu, Estonia
contact email	fazeli@emu.ee
lab head
SUBHASHINI MUHANDIRAM MUHANDIRAM RALALAGE
contact affiliation	Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences
contact email	soomuhandiram2@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD040311

PRIDE project URI

• PRIDE
  1. PXD040311
     1. Label: PRIDE project
     2. Name: SECRETORY PROTEOMIC RESPONSES OF ENDOMETRIAL EPITHELIAL CELLS TO TROPHOBLAST DERIVED EXTRACELLULAR VESICLES