PXD040300
PXD040300 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteome alteration of envenomed muscle in mice and the antidotal effect of a novel metalloproteinase inhibitor from Sinonatrix annularis |
| Description | Snakebite by Deinagkistrodon acutus often leads to severe tissue necrosis, hemorrhage and inflammation due to the high content of metalloproteinase (SVMP) and phospholipase A2 (PLA2). These impairments can be significantly alleviated by serum of Sinonatrix annularis, a nonvenomous snake endogenous in China. Here, the proteome alteration of envenomed mice were determined using TMT labeling technique to clarify the mechanism of D. acutus envenomation and S. annularis protection. |
| HostingRepository | iProX |
| AnnounceDate | 2023-02-21 |
| AnnouncementXML | Submission_2023-02-20_22:48:15.910.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Kepu Fu |
| SpeciesList | scientific name: Mus |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-02-20 22:47:41 | ID requested | |
| ⏵ 1 | 2023-02-20 22:48:16 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Snake venom metalloprotease, Deinagkistrodon acutus, Metalloprotease inhibitor, SaMPI, Sinonatrix annularis |
Contact List
| Chunhong Huang | |
|---|---|
| contact affiliation | College of Basic Medical Sciences, Nanchang University |
| contact email | chhuang@ncu.edu.cn |
| lab head | |
| Kepu Fu | |
| contact affiliation | College of Basic Medical Sciences, Nanchang University |
| contact email | kepufu@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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