PXD040298
PXD040298 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Deacetylation Induced Nuclear Condensation of HP1γ Promotes Multiple Myeloma Drug Resistance |
Description | Functional crosstalk between histone modifications and chromatin remodeling has emerged as a key regulatory mode of transcriptional control during drug resistance, but the underlying mechanisms are not fully understood. Here we demonstrate that different proteins and their acetylation modification regulate the resistance of multiple myeloma cells to BTZ. |
HostingRepository | iProX |
AnnounceDate | 2023-02-20 |
AnnouncementXML | Submission_2023-03-13_00:14:42.491.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Zhiqiang Liu |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-02-20 18:32:35 | ID requested | |
1 | 2023-02-20 18:55:29 | announced | |
⏵ 2 | 2023-03-13 00:14:43 | announced | 2023-03-13: Update publication information. |
Publication List
Li X, Wang S, Xie Y, Jiang H, Guo J, Wang Y, Peng Z, Hu M, Wang M, Wang J, Li Q, Wang Y, Liu Z, promotes multiple myeloma drug resistance. Nat Commun, 14(1):1290(2023) [pubmed] |
Keyword List
submitter keyword: Multiple Myeloma,HP1γ,Protein acetylation,DNA repair |
Contact List
Zhiqiang Liu | |
---|---|
contact affiliation | Tianjin Medical University |
contact email | zhiqiangliu@tmu.edu.cn |
lab head | |
Zhiqiang Liu | |
contact affiliation | Tianjin Medical University |
contact email | zhiqiangliu@tmu.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |