PXD040242

PXD040242 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Sleep deprivation exacerbates microglial reactivity and A beta deposition: TREM2-dependence in wild type mice and a model of amyloidosis
Description	We investigated whether sleep loss causes global changes in the proteome by analyzing cerebrospinal fluid using unbiased mass-spectrometry to identify proteolytic processes unique, or similar to changes linked to sleep and TREM2 genotype, in the presence or absence of A beta plaques.
HostingRepository	MassIVE
AnnounceDate	2023-04-27
AnnouncementXML	Submission_2023-04-27_04:52:27.984.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jim Malone
SpeciesList	scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090;
ModificationList	Carbamidomethyl; Oxidation; Deamidated; Gln->pyro-Glu; Pyro-carbamidomethyl
Instrument	timsTOF Pro

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-17 10:04:31	ID requested
⏵ 1	2023-04-27 04:52:28	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Sleep, Microglia, Amyloid, Alzheimers disease

submitter keyword: Sleep, Microglia, Amyloid, Alzheimers disease

Contact List

Samira Parhizkar
contact affiliation	Washington University in St Louis
contact email	psamira@wustl.edu
lab head
Jim Malone
contact affiliation	Washington University Sch
contact email	jmalone@wustl.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
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MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000091315/