PXD040232
PXD040232 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Directed Differentiation of Human iPSCs into Mesenchymal Lineages by Optogenetic Control of TGF-β Signaling |
| Description | For chondrogenic studies of optogenetically activated TGF-β signaling, optogenetic human iPSC-derived MSCs were encapsulated in hydrogels (20 million cells/mL of 2% agarose hydrogel). Groups received either no soluble TGF-β or optogenetic stimulation, or soluble TGF-β3 alone, or optogenetic stimulation alone. After 21 days of differentiation, we performed global quantitative proteomics on samples from two independent experiments, with n=3 replicates per group. |
| HostingRepository | PRIDE |
| AnnounceDate | 2024-10-22 |
| AnnouncementXML | Submission_2024-10-22_05:56:34.962.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Josephine Wu |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | ultraflex |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-02-17 03:42:35 | ID requested | |
| 1 | 2023-07-20 11:42:03 | announced | |
| 2 | 2023-11-14 09:03:40 | announced | 2023-11-14: Updated project metadata. |
| ⏵ 3 | 2024-10-22 05:56:37 | announced | 2024-10-22: Updated project metadata. |
Publication List
| Wu JY, Yeager K, Tavakol DN, Morsink M, Wang B, Soni RK, Hung CT, Vunjak-Novakovic G, signaling. Cell Rep, 42(5):112509(2023) [pubmed] |
| 10.1016/j.celrep.2023.112509; |
Keyword List
| submitter keyword: Human, iPSC, chondrogenesis, hydrogel, agarose |
Contact List
| Gordana Vunjak-Novakovic | |
|---|---|
| contact affiliation | Department of Biomedical Engineering, Columbia University, New York, NY 10032, USA Department of Medicine, Columbia University, New York, NY 10032, USA |
| contact email | gv2131@columbia.edu |
| lab head | |
| Josephine Wu | |
| contact affiliation | Columbia University |
| contact email | jw3566@columbia.edu |
| dataset submitter | |
Full Dataset Link List
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD040232 |
| PRIDE project URI |
Repository Record List
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