PXD040173

PXD040173 is an original dataset announced via ProteomeXchange.

Title	A Comparison of Quantitative Mass Spectrometric Methods for Drug Target Identification by Thermal Proteome Profiling
Description	Benchmarking different LFQ-DIA approaches with traditional TMT-DDA for thermal proteome profiling.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_09:10:42.854.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Matthias Trost
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-16 10:05:38	ID requested
1	2023-10-24 12:56:16	announced
⏵ 2	2023-11-14 09:10:46	announced	2023-11-14: Updated project metadata.

George AL, Sidgwick FR, Watt JE, Martin MP, Trost M, Mar, í, n-Rubio JL, Due, ñ, as ME, Comparison of Quantitative Mass Spectrometric Methods for Drug Target Identification by Thermal Proteome Profiling. J Proteome Res, 22(8):2629-2640(2023) [pubmed]

submitter keyword: hybrid library, target deconvolution, data-dependent acquisition (DDA), tandem mass tag (TMT),Thermal proteome profiling (TPP), acute myeloid leukaemia (AML), spectral library, data-independent acquisition (DIA)

Prof Matthias Trost
contact affiliation	Chair of Proteomics, Newcastle University Biosciences Institute, Medical School, Framlington Place, Newcastle-upon-Tyne, NE2 4HH, UK
contact email	matthias.trost@ncl.ac.uk
lab head
Matthias Trost
contact affiliation	Newcastle University
contact email	matthias.trost@ncl.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD040173

PRIDE project URI

• PRIDE
  1. PXD040173
     1. Label: PRIDE project
     2. Name: A Comparison of Quantitative Mass Spectrometric Methods for Drug Target Identification by Thermal Proteome Profiling