PXD040133
PXD040133 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic analysis on the role of ZBT21 |
| Description | We transfected the DNA fragments into hek293T cells, used beads to precipitate the DNA, eluted the DNA-binding protein, and performed quantitative mass spectrometry to identify that the ZBT21 protein specifically binds to cAMP response element. |
| HostingRepository | iProX |
| AnnounceDate | 2023-02-15 |
| AnnouncementXML | Submission_2025-06-17_19:50:12.668.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Muzhen Qiao |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | TripleTOF 5600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-02-15 18:51:06 | ID requested | |
| 1 | 2023-10-30 21:18:57 | announced | |
| ⏵ 2 | 2025-06-17 19:50:13 | announced | 2025-06-18: Add Publication. |
Publication List
| Qiao M, Huang Q, Wang X, Han J, ZBTB21 suppresses CRE-mediated transcription to impair synaptic function in Down syndrome. Sci Adv, 10(27):eadm7373(2024) [pubmed] |
Keyword List
| submitter keyword: ZBT21, DNA pulldown, cAMP response element |
Contact List
| Jiahuai Han | |
|---|---|
| contact affiliation | Xiamen University |
| contact email | jhan@xmu.edu.cn |
| lab head | |
| Muzhen Qiao | |
| contact affiliation | Xiamen University |
| contact email | qmzbrc@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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