PXD040132

PXD040132 is an original dataset announced via ProteomeXchange.

Title	Proteomic and phosphoproteomic analysis on skeletal muscle from Glut4 mutant mice
Description	This study aimed to investigate the effect of glucose restriction (GR) on energy metabolism and muscle fibre type in skeletal muscle. To achieve this goal, we constructed a mouse model of innate glucose restriction by mutating the glucose transporter 4 (Glut4), the major glucose transporter in skeletal muscle. We performed proteomic and phosphoproteomic analysis on gastrocnemius samples of male Glut4m mice at 12-week age, with or without a 4-week low-intensity training.
HostingRepository	iProX
AnnounceDate	2023-02-15
AnnouncementXML	Submission_2024-02-22_19:53:18.592.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kaiyi Zhang
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-15 18:30:05	ID requested
1	2023-11-15 19:39:09	announced
⏵ 2	2024-02-22 19:53:19	announced	2024-02-23: Update information.

Zhang K, Xie N, Ye H, Miao J, Xia B, Yang Y, Peng H, Xu S, Wu T, Tao C, Ruan J, Wang Y, Yang S, Glucose restriction enhances oxidative fiber formation: A multi-omic signal network involving AMPK and CaMK2. iScience, 27(1):108590(2024) [pubmed]

submitter keyword: mouse model, glucose restriction, Glut4, muscle fiber

Shulin Yang
contact affiliation	Institute of Animal Science, Chinese Academy of Agricultural Sciences
contact email	yangshulin@caas.cn
lab head
Kaiyi Zhang
contact affiliation	Institute of Animal Science, Chinese Academy of Agricultural Sciences
contact email	kaiyi.zhang1016@outlook.com
dataset submitter

iProX dataset URI