PXD040020

PXD040020 is an original dataset announced via ProteomeXchange.

Title	Musashi-type translational regulator controls the buildup of secondary cell wall in Arabidopsis
Description	Deciphering the mechanism of secondary cell wall/SCW formation in vascular plants is key to understanding their development and the molecular basis of biomass recalcitrance. Although a sophisticated network of transcription factors has been implicated in SCW synthesis in plants, little is known about the implication of RNA-binding proteins in this process. Here we report that two RNA-binding proteins homologous to the animal translational regulator Musashi, Musashi-Like2/MSIL2 and Musashi-Like4/MSIL4, function redundantly to control SCW formation in interfascicular fibers and the setting of biomass recalcitrance. We show that the disruption of MSIL2/4 (msil2-4 mutant) decreases the abundance of lignin in fibers and triggers an hypermethylation of glucuronoxylan that is linked to an over-accumulation of GlucuronoXylan Methyltransferase1/3 (GXM1/3) proteins.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:51:58.481.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD040020
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Yohann Couté
SpeciesList	scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-10 04:49:07	ID requested
1	2023-09-28 03:58:56	announced
⏵ 2	2023-11-14 08:51:58	announced	2023-11-14: Updated project metadata.

10.6019/PXD040020;

submitter keyword: Arabidopsis thaliana, secondary cell wall, RNA-binding proteins, nanoLC-MS/MS, post-transcriptional regulation

Yohann Couté
contact affiliation	EDyP
contact email	yohann.coute@cea.fr
lab head
Yohann Couté
contact affiliation	EDyP
contact email	yohann.coute@cea.fr
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD040020
     1. Label: PRIDE project
     2. Name: Musashi-type translational regulator controls the buildup of secondary cell wall in Arabidopsis