PXD040018

PXD040018 is an original dataset announced via ProteomeXchange.

Title	Interactome of activated BAX in Senescent Cells.
Description	We aimed to identify the interactome of activated BAX in the mitochondria of senescent cells. Our goal was to understand which factors can directly mediate the formation of BAX pores in senescent cells.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_09:13:30.820.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Karolina Szczepanowska
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-10 04:47:48	ID requested
1	2023-08-13 05:51:25	announced
2	2023-10-27 01:37:53	announced	2023-10-27: Updated project metadata.
⏵ 3	2023-11-14 09:13:40	announced	2023-11-14: Updated project metadata.

Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli MG, Riley JS, Cloix C, Hall-Younger E, Machado Espindola-Netto J, Jurk D, Lagnado AB, Sales Gomez L, Farr JN, Saul D, Reed R, Kelly G, Eppard M, Greaves LC, Dou Z, Pirius N, Szczepanowska K, Porritt RA, Huang H, Huang TY, Mann DA, Masuda CA, Khosla S, Dai H, Kaufmann SH, Zacharioudakis E, Gavathiotis E, LeBrasseur NK, Lei X, Sainz AG, Korolchuk VI, Adams PD, Shadel GS, Tait SWG, Passos JF, Apoptotic stress causes mtDNA release during senescence and drives the SASP. Nature, 622(7983):627-636(2023) [pubmed]

submitter keyword: mtDNA,cellular senescence, bax, mitochondria

Karolina Szczepanowska
contact affiliation	IMol Polish Academy of Sciences, Warsaw, Poland
contact email	k.szczepanowska@imol.institute
lab head
Karolina Szczepanowska
contact affiliation	Institute of Mitochondrial Disease and Ageing, Medical Faculty, University of Cologne
contact email	karolina.szczepanowska.phd@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/08/PXD040018

PRIDE project URI

• PRIDE
  1. PXD040018
     1. Label: PRIDE project
     2. Name: Interactome of activated BAX in Senescent Cells.