PXD040011

PXD040011 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Cerebellum PC O-GlcNAcylation TMT analysis
Description	The total protein in the sample was extracted, part of the sample was taken out for protein concentration determination and SDS-PAGE detection, the other part was taken out for trypsin enzymolysis and labeling, and then equal amount of each labeled sample was mixed for chromatographic separation. Finally, the sample was analyzed by LC-MS/MS and data analysis. After quality assessment and preprocessing, expression level analysis and function analysis were conducted respectively. Functional annotation analysis of the identified proteins was performed using several common databases. GO analysis, Pathway analysis and interaction analysis were conducted for the screened differential proteins, and correlation analysis, expression pattern clustering heat map and venn analysis were conducted for the data of the comparison group. In addition, according to the data situation, study the correlation or the part of interest, select the key proteins and their functions or pathways, and conduct subsequent key research and verification direction.
HostingRepository	iProX
AnnounceDate	2023-02-09
AnnouncementXML	Submission_2023-05-05_21:52:43.205.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xin Zhao
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-09 19:52:44	ID requested
⏵ 1	2023-05-05 21:52:43	announced

Publication List

Liu F, Li S, Zhao X, Xue S, Li H, Yang G, Li Y, Wu Y, Zhu L, Chen L, Wu H, O-GlcNAcylation Is Required for the Survival of Cerebellar Purkinje Cells by Inhibiting ROS Generation. Antioxidants (Basel), 12(4):(2023) [pubmed]

Liu F, Li S, Zhao X, Xue S, Li H, Yang G, Li Y, Wu Y, Zhu L, Chen L, Wu H, O-GlcNAcylation Is Required for the Survival of Cerebellar Purkinje Cells by Inhibiting ROS Generation. Antioxidants (Basel), 12(4):(2023) [pubmed]

Keyword List

submitter keyword: Cerebellum, Purkinje cell, O-GlcNAc, LC-MS

submitter keyword: Cerebellum, Purkinje cell, O-GlcNAc, LC-MS

Contact List

Haitao Wu
contact affiliation	Beijing Institute of Basic Medical Sciences
contact email	wuht@bmi.ac.cn
lab head
Xin Zhao
contact affiliation	Beijing Institute of Basic Medical Sciences
contact email	zhaoxin.1234@foxmail.com
dataset submitter

Full Dataset Link List

iProX dataset URI

iProX dataset URI