PXD039943 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The effects of silencing PCYOX1 on the proteome of murine fibroblast cells 3t3-L1 differentiated to adipocyte-like cells |
Description | In order to evaluate the impact of PCYOX1 deletion on adipogenesis, we applied a label-free mass spectrometry-based proteomic approach to compare the proteome of 3T3-L1 differentiated for 9 days to adipocytes after PCYOX1 gene silencing. Pcyox1 was silenced using shRNA lentiviral particles. Control cells were treated with shRNA lentiviral particles containing a negative construct. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:45:21.761.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD039943 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Erica Gianazza |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Synapt MS |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-02-08 02:02:28 | ID requested | |
1 | 2023-05-10 09:33:44 | announced | |
2 | 2023-11-14 08:45:59 | announced | 2023-11-14: Updated project metadata. |
⏵ 3 | 2024-10-22 05:45:23 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.6019/PXD039943; |
Banfi C, Mallia A, Ghilardi S, Brioschi M, Gianazza E, Eligini S, Sahl, é, n P, Baetta R, Prenylcysteine Oxidase 1 Is a Key Regulator of Adipogenesis. Antioxidants (Basel), 12(3):(2023) [pubmed] |
10.3390/antiox12030542; |
Keyword List
submitter keyword: 3T3-L1 cells, label-free mass spectrometry,PCYOX1 |
Contact List
Cristina Banfi |
contact affiliation | Proteomics and Metabolomics Unit, Monzino Cardiologic Center, IRCCS, Milan, Italy |
contact email | cristina.banfi@cardiologicomonzino.it |
lab head | |
Erica Gianazza |
contact affiliation | Centro Cardiologico Monzino |
contact email | erica.gianazza@cardiologicomonzino.it |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD039943
- Label: PRIDE project
- Name: The effects of silencing PCYOX1 on the proteome of murine fibroblast cells 3t3-L1 differentiated to adipocyte-like cells