PXD039915

PXD039915 is an original dataset announced via ProteomeXchange.

Title	The direct effect of mycophenolate mofetil on podocytes in nephrotoxic serum nephritis
Description	The goal of our study was to characterize glomerulus and particularly podocyte biology during MMF treatment in an immune-triggered proteinuric glomerulopathy. Therefore, nephrotoxic serum nephritis was induced in three-week old wild-type mice. On day 3, half of the mice were treated with MMF (100 mg/kgBW/d p.o.) (NTS+MMF) for one week, the other half of animals with vehicle (NTS+veh). A further group without induction and treatment served as controls (C). On day 10, we performed proteomic analysis of glomeruli.
HostingRepository	PRIDE
AnnounceDate	2023-08-30
AnnouncementXML	Submission_2023-08-30_01:00:19.749.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	PreranaWagle
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-07 13:41:11	ID requested
⏵ 1	2023-08-30 01:00:20	announced

Dataset with its publication pending

submitter keyword: super-resolution imaging, intracellular Ca2+ imaging, actin cytoskeleton, multiphoton microscopy, renal epithelial cell,immune complex-mediated glomerulopathy, mycophenolic acid, glomerular filtration barrier

AgnesHackl
contact affiliation	Pediatric Nephrology, Department of Pediatrics Faculty of Medicine and University Hospital Cologne, Kerpener Street 62, 50937, Cologne, Germany
contact email	agnes.hackl@uk-koeln.de
lab head
PreranaWagle
contact affiliation	CECAD Research Center
contact email	proteomics-facility@uni-koeln.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/08/PXD039915

PRIDE project URI

• PRIDE
  1. PXD039915
     1. Label: PRIDE project
     2. Name: The direct effect of mycophenolate mofetil on podocytes in nephrotoxic serum nephritis