PXD039898

PXD039898 is an original dataset announced via ProteomeXchange.

Title	Structure and antigenicity of divergent Henipavirus fusion glycoproteins
Description	A novel henipavirus (HNV) named Langya virus (LayV) was isolated in human patients in China in August 2022. It is closely related to Mòjiāng virus (MojV) and represents the first instance of HNV zoonosis to humans outside of Nipah virus (NiV) and Hendra viruses (HeV). Within this work, mass spectrometry glycoproteomic analysis revealed that although the LayV F protein has reduced glycosylation compared to its NiV and HeV counterparts, a unique glycan was identified positioned at the DIII apex, shielding a previously identified site of vulnerability in NiV F.
HostingRepository	PRIDE
AnnounceDate	2023-05-03
AnnouncementXML	Submission_2023-05-02_19:52:40.405.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	KyleMacauslane
SpeciesList	scientific name: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus); NCBI TaxID: 10029;
ModificationList	S-carboxamidoethyl-L-cysteine; monohydroxylated residue; deamidated residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-06 06:00:37	ID requested
⏵ 1	2023-05-02 19:52:40	announced

Dataset with its publication pending

submitter keyword: Glycoprotein,Henipavirus, Virus Structures

Benjamin L.Schulz
contact affiliation	School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia QLD, Australia, 4072 (lab head)
contact email	b.schulz@uq.edu.au
lab head
KyleMacauslane
contact affiliation	School of Chemistry and Molecular Biosciences, University of Queensland
contact email	k.macauslane@uq.net.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD039898

PRIDE project URI

• PRIDE
  1. PXD039898
     1. Label: PRIDE project
     2. Name: Structure and antigenicity of divergent Henipavirus fusion glycoproteins