PXD039887

PXD039887 is an original dataset announced via ProteomeXchange.

Title	C9orf72 ubiquitin and interaction proteomics
Description	C9orf72 binds SMCR8 to from a robust complex that regulates small GTPases, lysosomal integrity and autophagy. In contrast to this functional understanding, we know far less about assembly and turnover of the C9orf72-SMCR8 complex. Loss of either subunit causes the concurrent ablation of the respective partner. However, the molecular mechanism underlying this interdependence remains elusive.
HostingRepository	PRIDE
AnnounceDate	2023-05-10
AnnouncementXML	Submission_2023-05-10_05:29:59.237.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	ChristianBehrends
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-06 05:45:38	ID requested
⏵ 1	2023-05-10 05:29:59	announced

Dataset with its publication pending

submitter keyword: ALS, FTD, ubiquitin,C9orf72, SMCR8

ChristianBehrends
contact affiliation	Munich Cluster for Systems Neurology (SyNergy) Ludwig-Maximilians-Universität München Feodor-Lynen Strasse 17, 81377 München, Germany
contact email	christian.behrends@mail03.med.uni-muenchen.de
lab head
ChristianBehrends
contact affiliation	SyNergy, LMU München
contact email	christian.behrends@mail03.med.uni-muenchen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD039887

PRIDE project URI

• PRIDE
  1. PXD039887
     1. Label: PRIDE project
     2. Name: C9orf72 ubiquitin and interaction proteomics