PXD039873
PXD039873 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Extracellular vesicles play a central role in the cerebral deep medullary vein reduction-associated brain atrophy |
| Description | EVs were extracted from the serum of normal and DMV-reduction participants and compared their proteome profiles through a combination of liquid chromatography-tandem mass spectroscopy analysis and Tandem Mass Tag label quantitation analysis. In vitro assays were also conducted to access the impact of EVs on the reduction of vein number and brain atrophy, using serum-derived EVs to treat neurons, astrocytes, endothelial cells, and smooth muscle cells. |
| HostingRepository | iProX |
| AnnounceDate | 2023-02-03 |
| AnnouncementXML | Submission_2023-02-05_19:28:34.196.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Wei Ge |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-02-05 19:28:20 | ID requested | |
| ⏵ 1 | 2023-02-05 19:28:34 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Deep medullary vein, brain atrophy, extracellular vesicles, proteomics |
Contact List
| Wei Ge | |
|---|---|
| contact affiliation | Institute of Basic Medical Sciences Chinese Academy of Medical Sciences |
| contact email | gewei@ibms.cams.cn |
| lab head | |
| Wei Ge | |
| contact affiliation | Institute of Basic Medical Sciences Chinese Academy of Medical Sciences |
| contact email | gewei@ibms.cams.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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