PXD039845

PXD039845 is an original dataset announced via ProteomeXchange.

Title	Proteomics analysis of extracellular vesicles purified by heparin chromatography.
Description	Extracellular vesicles (EVs) were isolated from U2OS cell (Human) conditioned medium (Input) was fractionated into two subpopulations named non-heparin binding (NHB) and heparin-binding (HB). Proteomics analysis was performed on Input, NHB and HB samples. The two main goals for this analysis are: first, do a proteomics profiling study to identify proteins present in each of the 3 samples; second, perform quantitative analysis of the level of identified proteins in the samples and investigate if there is a certain enrichment pattern differences in samples "NHB" and "HB". Three biological replicates are included.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_09:00:50.330.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yijun Zhou
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Thermo Scientific instrument model

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-03 15:04:23	ID requested
1	2023-06-13 13:30:31	announced
⏵ 2	2023-11-14 09:00:50	announced	2023-11-14: Updated project metadata.

Dataset with its publication pending

submitter keyword: Extracellular vesicles, Proteomics, Heparin, LC-MS/MS

Dirk Dittmer
contact affiliation	Lineberger Comprehensive Cancer Center, Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
contact email	dirk_dittmer@med.unc.edu
lab head
Yijun Zhou
contact affiliation	University of North Carolina at Chapel Hill
contact email	yijun.zhou@med.unc.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD039845

PRIDE project URI

• PRIDE
  1. PXD039845
     1. Label: PRIDE project
     2. Name: Proteomics analysis of extracellular vesicles purified by heparin chromatography.