PXD039798

PXD039798 is an original dataset announced via ProteomeXchange.

Title	O-GlcNAcome of OGA stalk domain mutants
Description	THe O-GlcNAcome of OGA stlka domain mutation R586A and cancer derived mutation S652F in T-REx HEK293 cells
HostingRepository	PRIDE
AnnounceDate	2025-01-22
AnnouncementXML	Submission_2025-01-22_09:00:29.767.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chia-Wei Hu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; complex glycosylation; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-02-02 08:19:26	ID requested
⏵ 1	2025-01-22 09:00:30	announced

10.1073/pnas.2320867121;

Hu CW, Wang A, Fan D, Worth M, Chen Z, Huang J, Xie J, Macdonald J, Li L, Jiang J, OGA mutant aberrantly hydrolyzes O-GlcNAc modification from PDLIM7 to modulate p53 and cytoskeleton in promoting cancer cell malignancy. Proc Natl Acad Sci U S A, 121(24):e2320867121(2024) [pubmed]

submitter keyword: OGA, O-GlcNAc, stalk domain

Jiaoyang Jiang
contact affiliation	School of Pharmacy, University of Wisconsin-aAdison
contact email	jiaoyang.jiang@wisc.edu
lab head
Chia-Wei Hu
contact affiliation	Institute of molecular and cellular biology
contact email	hkmq8195@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD039798

PRIDE project URI

• PRIDE
  1. PXD039798
     1. Label: PRIDE project
     2. Name: O-GlcNAcome of OGA stalk domain mutants