PXD039651

PXD039651 is an original dataset announced via ProteomeXchange.

Title	Immunoreactive proteins of Capsicum-based spices as a threat to human health: mass spectrometry analysis and in silico mapping
Description	The identification of allergenicity of paprika proteins is important, especially those that could trigger a severe allergic reaction in patients with an equivocal clinical picture. In this study two types of protein extracts extracted from 3 different paprika spices were immunoblotted with the sera of patients displaying severe allergic symptoms, presumably to paprika. Proteins from the IgE-reactive bands obtained were subjected to LC-MS/MS identification and then to in silico analysis to verify their allergenicity and characterise their proinflammatory activity using online tools.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:26:32.492.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD039651
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Anna Ogrodowczyk
SpeciesList	scientific name: Viridiplantae; NCBI TaxID: 33090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2023-01-25 06:13:01	ID requested
1	2023-10-17 04:28:07	announced
⏵ 2	2023-11-14 07:26:32	announced	2023-11-14: Updated project metadata.
⏵ 2	2023-11-14 07:26:32	announced	2023-11-14: Updated project metadata.

10.6019/PXD039651;

submitter keyword: paprika, protein, allergy

Barbara Wróblewska
contact affiliation	Institute of Animal Reproduction and Food Research Polish Academy of Sciences
contact email	b.wroblewska@pan.olsztyn.pl
lab head
Anna Ogrodowczyk
contact affiliation	Institute of Animal Reproduction and Food Research, Polish Academy of Sciences
contact email	a.ogrodowczyk@pan.olsztyn.pl
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD039651
     1. Label: PRIDE project
     2. Name: Immunoreactive proteins of Capsicum-based spices as a threat to human health: mass spectrometry analysis and in silico mapping