PXD039425 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Characterization of L1 ORF1p macromolecular complexes from Mael-/- mouse testes |
Description | piRNA-deficient Maelstrom (Mael) null mice are characterized by a strong upregulation of retrotransposon LINE-1 (L1) in meiotic spermatocytes. This defect turns out in the accumulation of L1 RNA and ORF1p in their cytoplasm and the formation of prominent ribonucleoprotein aggregates. We used 3-months-old Mael-/- male mice to characterize the protein composition of those ORF1p aggregates. |
HostingRepository | PRIDE |
AnnounceDate | 2023-05-26 |
AnnouncementXML | Submission_2023-05-26_13:17:56.776.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | ChiaraDe Luca |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-01-13 07:26:14 | ID requested | |
⏵ 1 | 2023-05-26 13:17:57 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Mouse, retrotransposon LINE-1, ribonucleoprotein, germ cell, meiosis |
Contact List
AlexBortvin |
contact affiliation | Carnegie Institution for Science Dept. of Embryology 3520 San Martin Dr Baltimore, MD 21218 |
contact email | bortvin@carnegiescience.edu |
lab head | |
ChiaraDe Luca |
contact affiliation | Carnegie Institution for Science Embryology |
contact email | cdeluca@carnegiescience.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD039425 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD039425
- Label: PRIDE project
- Name: Characterization of L1 ORF1p macromolecular complexes from Mael-/- mouse testes