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PXD039425

PXD039425 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCharacterization of L1 ORF1p macromolecular complexes from Mael-/- mouse testes
DescriptionpiRNA-deficient Maelstrom (Mael) null mice are characterized by a strong upregulation of retrotransposon LINE-1 (L1) in meiotic spermatocytes. This defect turns out in the accumulation of L1 RNA and ORF1p in their cytoplasm and the formation of prominent ribonucleoprotein aggregates. We used 3-months-old Mael-/- male mice to characterize the protein composition of those ORF1p aggregates.
HostingRepositoryPRIDE
AnnounceDate2023-05-26
AnnouncementXMLSubmission_2023-05-26_13:17:56.776.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChiaraDe Luca
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-01-13 07:26:14ID requested
12023-05-26 13:17:57announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Mouse, retrotransposon LINE-1, ribonucleoprotein, germ cell, meiosis
Contact List
AlexBortvin
contact affiliationCarnegie Institution for Science Dept. of Embryology 3520 San Martin Dr Baltimore, MD 21218
contact emailbortvin@carnegiescience.edu
lab head
ChiaraDe Luca
contact affiliationCarnegie Institution for Science Embryology
contact emailcdeluca@carnegiescience.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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