Quantitative proteomic data for 10 stages (including 4-cell, 256-cell, 1000-cell, Oblong, Dome, Bud, 16-hpf, 28-hpf, 3-dpf, 5-dpf) of early zebrafish development, each stage corresponds to two sets of biological repeats, and each set of biological repeats corresponds to two sets of technical repeats.