PXD039304

PXD039304 is an original dataset announced via ProteomeXchange.

Title	Proteome-wide analysis and functional identification of lysine β-hydroxybutyrylation in Ustilaginoidea virens
Description	Lysine β-hydroxybutyrylation (Kbhb) is an evolutionarily conserved and widespread post-translational modification (PTM) in active gene transcription and cellular proliferation. However, its function remains unknown in phytopathogenic fungi. Here, we report a comprehensive identification of Kbhb in the rice false smut fungus Ustilaginoidea virens. Total 2,204 Kbhb sites were identified in 852 proteins. We found that β-hydroxybutyrylated proteins were enriched in mannose type O-glycan biosynthesis, citrate cycle (TCA cycle), ribosome, glycolysis/gluconeogenesis, proteasome, glyoxylate and dicarboxylate metabolism, alanine, aspartate and glutamate metabolism, pyruvate metabolism, biosynthesis of nucleotide sugars, butanoate metabolism, arginine biosynthesis, fructose and mannose metabolism, propanoate metabolism, methane metabolism, fatty acid degradation, β-alanine metabolism, valine, leucine and isoleucine degradation, phagosome, oxidative phosphorylation pathway. This suggests Kbhb might be involved in basic life functions of Ustilaginoidea virens.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_09:07:48.646.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xiaoyang Chen
SpeciesList	scientific name: Ustilaginoidea virens; NCBI TaxID: 1159556;
ModificationList	O5-galactosyl-L-hydroxylysine
Instrument	timsTOF

Revision	Datetime	Status	ChangeLog Entry
0	2023-01-06 06:47:10	ID requested
1	2023-10-24 11:33:22	announced
⏵ 2	2023-11-14 09:07:58	announced	2023-11-14: Updated project metadata.

Chen X, Duan Y, Ren Z, Niu T, Xu Q, Wang Z, Zheng L, Wang Y, Chen X, Huang J, Pan Y, -Hydroxybutyrylation Regulates Ustilaginoidea virens Virulence. Mol Cell Proteomics, 22(8):100616(2023) [pubmed]

submitter keyword: Lysine β-hydroxybutyrylation

post-translational modification

Ustilaginoidea virens

virulence

Xiaoyang Chen
contact affiliation	College of Plant Protection, Anhui Agricultural University
contact email	1149806052@qq.com
lab head
Xiaoyang Chen
contact affiliation	The Key Lab of Plant Pathology of Hubei Province, Huazhong Agricultural University, Wuhan 430070, China
contact email	1149806052@qq.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD039304

PRIDE project URI

• PRIDE
  1. PXD039304
     1. Label: PRIDE project
     2. Name: Proteome-wide analysis and functional identification of lysine β-hydroxybutyrylation in Ustilaginoidea virens